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  • MRI, hybrid imaging outperform conventio

    From ScienceDaily@1:317/3 to All on Thu Dec 9 21:30:46 2021
    MRI, hybrid imaging outperform conventional tests for small cell lung
    cancer staging
    MRI, with or without FDG PET coregistration, can improve the staging of patients with small cell lung cancer

    Date:
    December 9, 2021
    Source:
    American Roentgen Ray Society
    Summary:
    MRI -- with or without FDG PET coregistration --c an improve the
    staging of patients with small cell lung cancer.



    FULL STORY ========================================================================== According to an article in ARRS' American Journal of Roentgenology (AJR),
    MRI - - with or without FDG PET coregistration -- can improve the staging
    of patients with small cell lung cancer (SCLC).


    ==========================================================================
    "FDG PET/CT, whole-body MRI, and coregistered FDG PET/MRI outperformed conventional tests for various staging endpoints in patients with SCLC," concluded first author Yoshiharu Ohno from the Fujita Health University
    School of Medicine in Japan. Whole-body MRI and FDG PET/MRI outperformed
    FDG PET/CT for T category and thus TNM stage, "indicating utility of MRI
    for assessing extent of local invasion in SCLC." Ohno and colleagues' prospective study included 98 patients (64 men, 34 women; median age,
    74 years) with SCLC who underwent conventional staging tests (brain MRI;
    neck, chest, and abdominopelvic CT; bone scintigraphy), FDG PET/CT,
    and FDG PET/MRI within 2 weeks before treatment. After MRI technologists performed coregistration via proprietary software (Canon Medical Systems),
    two nuclear medicine physicians and two chest radiologists independently reviewed the examinations in separate sessions.

    In patients with SCLC, accuracy for T category was higher (p<.05) for
    whole- body MRI (94.9%) and FDG PET/MRI (94.9%) than for FDG PET/CT
    (85.7%).

    Meanwhile, TNM stage accuracy was higher (p<.05) for whole-body MRI
    (88.8%) and FDG PET/MRI (86.7%) than for FDG PET/CT (77.6%) and
    conventional staging tests (72.4%).

    "These additional observations may relate to a superior role of MRI
    in assessing the extent of local soft tissue invasion by tumor, as has
    been observed in settings other than SCLC," added the authors of this
    AJR article.

    ========================================================================== Story Source: Materials provided by American_Roentgen_Ray_Society. Note: Content may be edited for style and length.


    ========================================================================== Journal Reference:
    1. Yoshiharu Ohno, Takeshi Yoshikawa, Daisuke Takenaka, Hisanobu
    Koyama,
    Kota Aoyagi, Masao Yui, Yuka Oshima, Nayu Hamabuchi, Yumi Tanaka,
    Chika Shigemura, Seiichiro Oota, Masahiko Nomura, Kazuhiro
    Murayama, Yoshitaka Inui, Kaoru Kikukawa, Hiroshi Toyama. Small
    Cell Lung Cancer Staging: Prospective Comparison of Conventional
    Staging Tests, FDG PET/CT, Whole- Body MRI, and Coregistered
    FDG PET/MRI. American Journal of Roentgenology, 2021; DOI:
    10.2214/AJR.21.26868 ==========================================================================

    Link to news story: https://www.sciencedaily.com/releases/2021/12/211209095634.htm

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