Psychiatric disease associated with increased risk of death from cardiovascular disease and diabetes

Date:
January 27, 2022
Source:
PLOS
Summary:
Among patients with chronic, non-communicable diseases, the risk
of death is more than doubled if they also have a psychiatric
comorbidity, according to a new study.



FULL STORY ========================================================================== Among patients with chronic, non-communicable diseases, the risk of
death is more than doubled if they also have a psychiatric comorbidity, according to a new study publishing January 27th in PLOS Medicineby
Seena Fazel of the University of Oxford, UK, and colleagues.


========================================================================== Non-communicable diseases such as diabetes and heart disease are a global public health challenge accounting for an estimated 40 million excess
deaths annually. In the new study, researchers used national registers in Sweden to investigate more than 1 million patients born between 1932 and
1995 who had diagnoses of chronic lung disease, cardiovascular disease,
and diabetes. More than a quarter (25-32%) of people in the analysis
had a co-occurring lifetime diagnosis of any psychiatric disorder.

Within 5 years of diagnosis, 7% (range 7.4%-10.8%; P<0.001) of the people included in the study had died from any cause and 0.3% (0.3%-0.3%;
P<0.001) had died from suicide. Comorbid psychiatric disorders were
associated with higher all-cause mortality (15.4%-21.1%) when compared to
those without such conditions (5.5%-9.1%). When the researchers compared
each patient with an unaffected sibling, to account for familial risk
factors, psychiatric comorbidity remained consistently associated with
elevated rates of premature mortality and suicide (adjusted HR range:
aHRCL=7.2 [95% CI: 6.8-7.7; P<0.001] to aHRCV =8.9 [95% CI: 8.5-9.4;
P<0.001]). Risks ranged by psychiatric diagnosis; for instance, mortality
risks were elevated by 8.3-9.9 times in those with comorbid substance
use disorder compared to unaffected siblings, and by 5.3-7.4 times in
those with comorbid depression. One limitation of the study is that
the use of population-based registries to identify patients means that psychiatric comorbidities were diagnosed in specialty care settings
and that undiagnosed individuals and those with less severe psychiatric
illness could be missed.

"Improving assessment, treatment, and follow-up of people with comorbid psychiatric disorders may reduce the risk of mortality in people with
chronic non-communicable diseases," the authors say.

"We used electronic health records to investigate over 1 million
patients diagnosed with chronic lung diseases, cardiovascular
diseases, and diabetes," Fazel adds. "More than 7% of the patients
died of any cause within five years and 0.3% died from suicide --
risks that were more than doubled in patients with psychiatric
comorbidities compared to those without such comorbidities."
special promotion Explore the latest scientific research on sleep and
dreams in this free online course from New Scientist -- Sign_up_now_>>> ========================================================================== Story Source: Materials provided by PLOS. Note: Content may be edited
for style and length.


========================================================================== Journal Reference:
1. Amir Sariaslan, Michael Sharpe, Henrik Larsson, Achim Wolf, Paul
Lichtenstein, Seena Fazel. Psychiatric comorbidity and risk
of premature mortality and suicide among those with chronic
respiratory diseases, cardiovascular diseases, and diabetes
in Sweden: A nationwide matched cohort study of over 1 million
patients and their unaffected siblings.

PLOS Medicine, 2022; 19 (1): e1003864 DOI:
10.1371/journal.pmed.1003864 ==========================================================================

Link to news story: https://www.sciencedaily.com/releases/2022/01/220127141616.htm

--- up 7 weeks, 5 days, 7 hours, 13 minutes
* Origin: -=> Castle Rock BBS <=- Now Husky HPT Powered! (1:317/3)