Increase in fatal opioid overdoses after hospital discharge

Date:
October 5, 2021
Source:
PLOS
Summary:
The period after hospital discharge is a high-risk time for
people who use illicit opioids such as heroin, according to new
research. Fatal opioid overdoses are four times more likely in
the first two days after hospital discharge than at other times,
and people who use illicit drugs need extra support when being
discharged from hospital.



FULL STORY ==========================================================================
The period after hospital discharge is a high-risk time for people
who use illicit opioids such as heroin, according to new research
publishing October 5th in the open access journal PLOS Medicine. Fatal
opioid overdoses are four times more likely in the first two days after hospital discharge than at other times, and people who use illicit drugs
need extra support when being discharged from hospital.


==========================================================================
The number of deaths related to opioids, such as heroin, is increasing in England. Hospital patients who use drugs often report undertreated pain
and opioid withdrawal and may leave hospital to use illegal drugs. Dan
Lewer of University College London and colleagues examined whether
hospital admission and discharge are associated with increased risk
of fatal drug overdoses, hoping to understand if these times present opportunities to support individuals who use illicit drugs.

They studied opioid-related deaths in England in people aged 18-64
using 2010- 2019 data from a national database. A total of 13,609 deaths occurred in that period, with 236 (1.7%) following drug use while admitted
to hospital:a risk that was smaller or lower than periods not in hospital
or recently discharged.

1,088 (8%) deaths occurred in the 14 days after hospital discharge, particularly during the first two days, which is an increase over
other periods. Patients who were admitted to hospital for psychiatric admissions, who left the hospital against medical advice or who had
stays of seven days or more were at greater risk.

The team concludes that with 1 in 14 opioid-related deaths in England
occurring in the two weeks after hospital discharge, interventions
such as treatment to prevent withdrawal or overdose response training
could save lives. "We don't want patients needing to treat their
own withdrawal or pain and end up overdosing in the bathroom,"
says co-author Thomas Brothers, who specializes in addiction
medicine. "Hospitals can do more to support this patient group,
by giving medicines such as methadone, safer consumption spaces,
take-home naloxone kits, and improving training." Lewer adds, "Drug
related deaths are a public health crisis in the UK. We can cut the
number of deaths by supporting people at the most difficult times. This
study shows that hospital discharge is one of those critical moments." ========================================================================== Story Source: Materials provided by PLOS. Note: Content may be edited
for style and length.


========================================================================== Journal Reference:
1. Dan Lewer, Brian Eastwood, Martin White, Thomas D. Brothers, Martin
McCusker, Caroline Copeland, Michael Farrell, Irene Petersen. Fatal
opioid overdoses during and shortly after hospital admissions in
England: A case-crossover study. PLOS Medicine, 2021; 18 (10):
e1003759 DOI: 10.1371/journal.pmed.1003759 ==========================================================================

Link to news story: https://www.sciencedaily.com/releases/2021/10/211005175359.htm

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