• I value and appreciate David Pearce' Hedonistic Imperative as well as A

    From Treon Verdery@21:1/5 to All on Thu Sep 8 01:05:26 2022
    Just smiling is published as causing better mood, at voluntary humans at the 90th percentile of feeling this effect, they could anesthetize the differentfacial muscles, then find out if it is a specific facial muscle that causes this effect, they could
    then find out if localization is possible and if putting neuroactors at that muscle to find out if people feel good all day, if they do then they could find out what brain regions that connects to and develop brain localized, neurotransmitter particular
    chemicals as drugs that cause the improved mood from smiling effect

    Longevity technology
    Epithalon AEDG peptide is published as causing 24% greater longevity at rodents, they could find out if body side and CNS side versions also cause greater longevity and then heighten the dosage to produce the greatest longevity as well as do genetic
    studies on both gene activation and what gene products are produced to find out which cause longevization, the gene products could be tested as enteric coated protein drugs to find out which, if any, are longevity increasing drugs, epigenetic drugs that
    effect those drugs could also be multigeneration longevity drugs

    Epithalon, AEDG, may have greater longevity and healthspan effects when taken at AM or PM, probiotics bacteria that sense GI tract temperature and motion diurnal variation could be produced that produce epithalon at different times and tested as to their
    longevity difference at age batched human voltuneteers, age batched marmosets, as well as rodent, I perceive I read there are healthspan and wellness and being more likely to be alive after 6 years (coadministered with the peptide thymosin) effects at
    humans from about 1 mg per 24 hours, administered for 14 days, perhaps twice annually, a probiotic that only produced 767 micrograms/24 hours would cumulatively deliver the same dose, and a version of the probiotics tested on rodents to find out what
    daily dose of epithalon from probiotics causes the greatest increase in longevity, the epithalon at the probiotics could have a GI tract passing peptide attached to it to pass GI tract membranes, and the GGG enzymatically degradeable linker be
    enxymatically removed at the circulatory system, D amino acids could also be used to find out if the 24 versions (4 factorial) of one to all four amino acids being D amino acids causes greater longevity than 24% while being orally available as a pill,
    liposomal enteric coated pills are also possible

    AEDG epithalon could effect particular receptors, I read immunizing against receptors can cause them to be continuously upregulated or down regulated immunizing to beneficially increase longevity and healthspan could be possible and tested on rodents
    before making a human immunization that longevizes for decades or a lifetime with one, possibly oral or snortable dose, similarly alpha 2 estradiol dosing causes mice to live 19% longer, immunizing to activate alpha 2 estradiol receptors could be a
    lifetime one dose longevity treatment, noting the longevity increase could offset any cancer risk, screening a library of alpha 2 estradiol molecular variants could find a molecular variant that is cancer neutral or reduces risk of cancer to be utilized
    as a longevity increasing drug

    Alpha 2 estradiol receptors could have localization possibilities, finding the organs and tissues most linked to the longevization effect could be of benefit at creating other new longevity drugs

    Enyerosorbents cause near 40% greater longevity, they could use polymaths cry late similar enyerosorbents to find out if this is a stomach effect, a small intestine effect or a colon effect and then develop new longevity treatments

    At large mammals does dialysis of any plasma fraction increase longevity, if it does then that suggests things which if immunized against could cause greater longevity

    Things that fill children with happiness
    It is possible children respond happily to humor, online screening with slider bars could find humor that makes children happy, it is possible children respond particularly well to particular kinds of humor at different ages, and people or AI could write
    humor for children, it is also possible children like making humorous statements and brief humororous statements that are easy to remember would be enjoyed by both children and adults are possible

    Gum disease is linked to cardiovascular risk, they could make protein and other chemical concentrates from gum disease bacteria and homogenate of diseased gums from large mammals and test them on mice and rabbits to find out which chemical components are
    associated with cardiovascular risk and create immunizations against them for use at humans

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