• The saliva tooth rebuilding and restoration capacity may have a genetic

    From Treon Verdery@21:1/5 to All on Fri Sep 30 10:14:44 2022
    Gene therapy at the teeth, tooth nerves and gums might be particularly easy to do and be durable for any gene therapy purpose

    The people with what is called superior autobiographal memory may have some shared genetic variation like alleles or SNPs, genes from people with superior autobiographical memory that are well and above the 90th percentile of happiness and placing those
    at mice and seeing if they remembered last years, or 2 years ago's learning of what they previously learned could find enhanced genetics of human memory beneficial to put at all humans, that is persons, that is people, as well as new gene therapies and
    drugs, notably people would get even more out of education

    I have read about using air emitting surfaces at airplanes to enhance aerodynamics with active control surfaces, I also read that flying at higher altitudes uses less fuel because there are fewer air molecules, it is just possible that air emitting
    aircraft surfaces or helicopter propellors or watercraft propellors that emit lower than ambient concentrations of air (similar but slightly different than PSI), at high enough velocities (like an air hockey table) could heighten fuel efficiency

    Some person figured out that scooters and few-person single cabin people movers (kind of like light rail cars) can increase fuel efficiency and scheduling flexibility, with computer/AI pilots it is possible humans travelling on multi person ultralight
    aircraft (as they are classed) could be more fuel efficient, and airport size and scheduling flexible, also the aircraft parts are smaller and easier/cheaper to build

    I perceive that paranormally knowledgeable, or even just paranormally educated people can arrange objects or do things that cause benefit, even benevolent benefit from what I call pattern resonance as I do not know its actual name, an AI (artificial
    intelligence), possibly a deep learning AI noting those AI that learn without precoded algorthmic specificity processing of all human actions and environment the video of a municipality, a townn and a forest dweller could use object finding and word
    recognition and quantified human occurrences over different timescales of varying orders of magnitude at deep learning to find completely new to published occurrence effect relationships at what I describe as pattern resonance, that are absent a 20th
    century mechanistic explanation, one JY described is that getting new shoes causes men to get new girlfriends or new sex partners more frequently or also more rapidly, one I am just making up is that putting a book with the title romantic success with a
    box of candy on it on top of a white electrical power supply and then eating a candy a day would increase the romantic advantage and frequency of women, testing JY's technology is likely to be more effective

    They could find the 99th percentile of pleasant psychology word: arousal with phone software and fMRI, then use those to build other technologies, like effective greetings and awards, hugs, beautiful happy people, and amusement parks and amusement park
    rides cause pleasant arousal moments in me, this could also replace negative advertising and possibly aversive material at videos, films and written media where the attention and amplitude of emotion at written or typed materials is valued, notably
    commercially valued

    The most affordable microcontroller (more capable than, but similar to a CPU) I found as the first link on a search is 23¢, at 14-20¢ to manufacture they could make a datalogger that records system diagnostics and voltage levels and frequencies with
    much more memory for the same or even less, placing this at utility meters, any device where people contest accuracy above 5$ is beneficial, 64 mb is a logged system snapshot every half second, and 64 mb is just 42/1000ths of a cent or less at a retail 1
    TB flash drive, so it could still be 14¢-23¢

    An opiate peptide, or a GABA active peptide could be molecularly attached to a sex hormone at microgram dosage amounts to preclude or treat menstrual cramps because the uterus would omit contracting and, I think, localizes concentrations of sex hormones
    at the uterus, at peptide quantities inkjet printed paper mini-squares could be 1/40th of a cent each

    Fluorinated and/or ethynylized and or peptide that localizes to the brain moietyed as well as cytomembrane passing peptide moeityized LSD and MDMA would be perhaps femtograms (LSD) or pictograms(MDMA) to 4 micrograms per dose and, at the dose form of one
    nerds(tm) candy volume would be, at 3700 Nerds per $1 1/3700th of a cent per LSD or MDMA equivalent dose

    LSD and MDMA enhanced localization moiety versions enshelled in micelles, with the micelles having cytomembrane transport peptides make the original drug molecule more affordable as well, it is possible a variety of different recreational drugs could be
    micronized causing them to be several orders of magnitude more affordable, attaching brain localization peptides, cytomembrane passing moieties, or and also harmless loose-fitting antibodies to neuron membrane surface proteins on the exterior of the
    micelle would localize the recreational drugs to the brain, the micelles could be taken orally, micelles with holes (whiffle ball) or polymer stripes that disintegrate from enzymatic effects only inside the neurons could provide a Rush feeling even if
    the dose was taken orally

    At a variety of therapeutic, recreational and better than well drugs as well as immunizations, RNA drugs and possibly gene therapy drug containing micelles with enzymatically degradable stripes, dissolving shell layers or even the published
    electromagnetically switchable and organ localizable medical gold nanoantennas could be optimized as to the velocity of onset or action, concentration of delivered drug, and chronologically custom shaped waveforms, pulse amplitude and shape at longevity
    drugs or and also recreational drugs that just keep getting perceptually higher and higher and more pleasing then stop, leaving you clear headed)

    A two chamber micelle or an "8" shaped micelle festooned with localization and cytomembrane transport moieties could have a get high (recreational drug) drug on one chronological schedule and a get sober drug or molecule disintegrating enzyme in the
    other chamber, when each of the chambers dissolves, possibly from either different enzymes or different micelle thicknesses then the high is converted to clear headedness and possibly neural healing or a return to prestimulated state, reducing a dosage
    escalation to keep getting high effect, or a maintenance dose prompting effect

    Dopamine is a neurotransmitter that does not pass the blood brain barrier, dopamine is associated with feelings of excitement and reward and pleasure, delivered to neurons with cytomembrane passing and brain area moieties or and also neuron localization
    moieties micelles containing dopamine could be variously a therapeutic drug, an antidepressant, and a recreational get high drug, this micelle full of neurotransmitters is likely also a technology at a variety of other neurotransmitters as well

    Things that make children happy, putting a wide variety of combinable faces and body forms at 3D VR headsets and giving them surface samples to touch at just 7 styles of head, 7 styles of body SA, 7 styles of limbs and 7 special effects is much more than
    39 million combinations (11 factorial) so along with the VR play testers they could have a webpage or click able ads to reach 39 million different reaction responses from children, the 99.99th percentile of most liked doll or toy shapes online would be
    3991 toy models produced in an automatic scripted way with CAD testable by 11 children in one day

    Neural network learns toy part preferences from 11 sampled children touching actual textures and seeing toy parts, a panel of 7 touchable textures like pen grip rubber, doll face rubber, stretch Armstrong fleshiness, doll face plastic, a couple
    engineering resins, microplush ultrasoft cloth, wood, as well as many others could be tested, at 11 seconds per preassembled panel of actual touchables, with measurement where two reusable music style keyboards where you press any key along its length to
    indicate how spontaneously fun it is (one keyboard) and if your mood (relative happiness) and feeling of funness went up or down (the other keyboard) when you touched it (this is similar to a slider bar test), that is tested, each child can view and
    tactilely test 411 textures (or toy parts) in four hours with two hours of each four taken out for refreshment breaks, and they can quit anytime, the 11 children testing toy parts (7 for a week that is 4525 funness and happiness measures per 2 hours of
    touching per day (11 children), or data 49,000 different data points the AI deep learning can learn from, get various 99.9th percentiles at, find the foci if there are multimodal distributions, find trends at, combining this with the website/ad data on
    the 99.99 the percentile of 39 million of preferred body forms produces new dolls and toys, and new design material trends and forms that make children happy and have fun

    The neural network toy preference dataset could even make 3D printed toys happier and more fun as well as making toys crafted by social companion robots even happier and dinner

    WiFi toys and dolls, these are likely already in development, a WiFi toy could automatically download 99th percentile funness of activity or a 99th percentile educational lesson plan (from a populous website with a rating system) when it wasn't being
    used, the cheapest WiFi chip on board I found online was 39¢, it could voice material, use the cloud and AI to do smarter things and sing songs from your CPU speaker (like Alexa echo dot)

    Plywood and particle board have a glue component, I think I have seen particle board with sparser core density, but I am not aware of plywood with foamed glue, requiring less glue, foaming glue at plywood and particle board would use less glue, permit
    cheaper fillers like clay or gypsum or even microgravel and make building materials more affordable, also, just like railroad ties with eentsy metal end caps on them plywood or particle board with mineral or concrete infused edges might be more durable
    and have greater dimensional stability and flexion strength at construction

    Babies like breasts, and humans like food, but humans like sweetened food more, sweetness peptides are published that are 200,000 times sweeter than sugar, to encourage babies that have trouble latching on, and for mothers that might notice their babies
    are happier with a sweeter treat, orally available sweetness peptides at a maternal dose of 1.5-3 micrograms a day would sweeten breastmilk, they could attach a beneficial to babies, children, and adults peptide, possibly a growth peptide, epithalon,
    thymosin, a pineal peptide, a tissue healing peptide or and also a nootropic, they could test the sweetness peptide combination or concatenated peptide on rodents, monkeys, and farm animals first, it could even get veterinary use first and the data that
    the combo peptide was bodyweight harmless and otherwise harmless to analogous child and adult farm animals throughout their lifetime, also noting any benefits, thymosin and epithalon, I read at a non peer reviewed description reduces infectious disease,
    thymosin, one of several thymus peptides thymosin alpha 1, is published at one study in a peer reviewed journal as being prophylactic against infection, making the copeptide (or on string peptide) cyclized with D amino acids could make it so it actually
    beneficially reaches the baby, peptides can be made into a slurry with tasteproof enteric coating formulas and put in gummy one a day pleasant tasting chewable gems, if infection preventing, combined with milk sweetening peptides are harmless and
    beneficial to babies they could also be placed at 1/10-1/40th of a cent a dose inkjet printed paper minidots and be affordable globally

    Increasing the potency per dose of a breast milk sweetening infection preventing combination peptide could possibly go with attaching it to a galactogen (causes greater breast milk supply), there are drug galactogens as well as galactogen chemicals in
    fenugreek, microgram doses, molecularly attached to the anti infection peptide could localize the anti infection peptide

    It is possible that a continent spanning rescue assistance radio could fit in the size of a kefob a long monofilament infused with soluble ions is infused with salt or other things that make ions to make a long conductive antenna (saltwater antennas are
    published) and is solar powered, a 6 farad capacitor is 50¢ on alibaba.com, and, I think, raise a 200 milliwatt current trickling in from the photovoltaic to several watts, if 5 watts can be achieved then that is ham radio wattage and that crosses
    continents, and sometimes the world, as the multifarad capacitor multiwatt pulse is very short something like a one millisecond data chirp, possibly encoding bank balance and words that say rescue will be financially remunerated, that can be received,
    there are already ham radio operators that scan rescue activity and are likely to willingly pass on rescue information and multi-ham triangulation data at a website, the user optimally flings part of the key fob over a tree or otherwise elevates the
    antenna, perhaps semiconductors could handle the data chirp, or, I read about non silicon high wattage other element semicondors, alternatively a very widely spaced data chirp could have just a few bigger transistors and send just a few bits of the data
    per second (tinyURL) and the ham radio accumulates a full reception

    A money sending site that asks the rescuer numerous identification questions could be beneficial at key fob radio rescue

    There are numerous bioactive plant peptides, some may benefit trees, flowers, agriculture,fruit, vegetables and herbs, it is possible the peptides at 1/100¢ to 1¢ a dose, screening a library could be done in a season, or, with duckweed in 24 hours (111
    96 well plates is 418,000 peptides screened annually), they could make systematic variations, mass screen, and find out if any have greater potency, some effect tissue differentiation, sugar (sucrose) metabolism,length flowers last, herbivore defense, "
    it is involved in vascularization, longitudinal cell expansion and increased radial expansion", what other plants a plant will breed with, auxin (growth chemical), "promote cellular proliferation and transdifferentiation", "maintain stem cell homeostasis"
    , systematically (amino acid substitution) varying these and screening a library could also find down regulating placeholder variants causing some beneficial effects to go up, extended release plant sprays exist, it is possible there is a string of
    multiple peptides that when genetically engineered into mycorhizial bacteria causes all plants to thrive and be more fecund https://en.m.wikipedia.org/wiki/Plant_peptide_hormone

    Framing lumber could have long holes drilled in it to have data communications paths like optical fiber run through it, flexible shaft drilling could even make it so the optical fiber curved up to reach the face of the lumber

    They could make a geotextile with electret or piezoelectric polymers that repel mud where you just build a circle of it in a swamp and it makes (perfuses) an area of clear calm water which is pretty but can be used for a variety of purposes

    Some debit cards could have a display on them, perhaps three digits, at the right side of the card that light up with each card reader transaction or on phones, this would provide 1000 variations, just at that one machine once making the card more secure,
    the display could be LED embedded in the plastic like the chip and powered by the card reader, two wrong guesses would turn the card off for 4 hours

    A woman with a variety of superheating was diagnosed with "diagnosed her with bilateral superior semicircular canal dehiscence. The rare condition means that Gemma is missing part of a tiny temporal bone in both her ear canals" suggesting that the
    genetics of normal ear anatomy could be enhanced to provide superhearing and greater frequency range, engineerable to benefit music appreciation

    Measuring the beauty appreciation of tetrachromats that see more colors and measuring the beauty perception of non tetrachromats tetrachromats at the 99.9th percentile of beauty appreciation at the non tetrachromat population could have genetics of
    enhanced beauty appreciation, making enhanced beauty perception a component of all persons' genetics is beneficial, another technology is to find the beneficial brain genetics of the 99th percentile of beauty appreciation among people also at the 99th
    percentile of happiness (quantified with psychometrics, possibly also AI interpreted fMRI of subjective well being, they could use psychometrics first, then find the different brain anatomy styles of beauty appreciation with fMRI), among the 99th
    percentile of wellness and happiness, perhaps detectable from scanning social media there is also a 99th percentile of enjoyed performance at touch, sight, taste, smell, and hearing which is beneficial to make a part of all humans, that is persons'
    genetics

    A handbag with a flexible OLED or Quantum LED display, or even just an iPhone touchscreen display element that is Bluetooth connected to your bag contained actual phone on its exterior, when not in use the exterior displays patterns that harmonize with
    the bags visual design, the handbag would do wireless recharging

    Parents loving their children has a 99th percentile, as do children making people happy, as does g (like IQ), one out of every 100,000 2019 persons (or more, they might overlap), screening each billion persons on social media and internet of things would
    find 10,000 of them and they have a partially genetic basis, combining them and making those components part of the genetics of all persons, that is people, that is humans is beneficial

    Prestressed glass resists breaking (like Corian(tm)), cofocalized lasers or bulk sheet dot holography that installs distributed prestressed patterns could make this effect even stronger (possibly like prince Rupert's drops with their tails all at the
    interior could work)

    Fetuses may produce proteins and peptides that contribute to or cause pregnancy to continue, supplementing the mother with those chemicals during pregnancy could cause more of the intended pregnancies that occur from the first month on to continue, that
    this benefits the child and adult and also is absent wellness problems is very important, genetics of these chemicals may also exist and be beneficial components to enhance all female persons

    Science museums and other museums could have "get the app" QR codes at their exhibits, all the graphics and text at the museum from some of the exhibits could be loaded and the ones they actually imaged could be top loaded at the first page, it could
    also make a tappable index unique to each user

    Kindergardens and early grades and Montessori schools and Waldorf schools often have enrichment or play areas, they could use video to record usage patterns and have AI process all the video to find the 99th percentile of the children spontaneously
    seeking out the most educational and fun activities, then making those room plans available

    The appendix could be a reservoir of beneficial bacteria genetically engineered to make beneficial probiotics that make vitamins and science phrase essential amino acids, installed with outside of body sonication or steerable pills, possibly that
    recolonize the colon from gradual release from the pill over years, another approach is to have the probiotic bacteria make proteolytic enzymes and lipid membrane degrading enzymes that optimally only work on one species of bacteria like ecoli, or even
    host viruses that wipe out E. Coli and not the human body, releasing nutrients that feed the probiotics for even longer, this could benefit people globally, they could even make longevity increasing chemicals

    AI could look at prerepair potholes and postrepair potholes with video and possibly interferometry and find the 99.9th percentile of pothole fill smoothness and durability then have the pothole filling equipment duplicate those filling styles where they
    are applicable, pothole filling machines could have multiple hoppers of different materials to customize the pothole filling, I think there is a sweet spot between concrete where the material around it thins out to a bump and asphalt that degrades to a
    hollow, the AI blending that sweet spot from the hoppers would make better pothole fills, there is also the possibility that 3D printing of ultraffordable materials could make really durable mini structures that match the surface durably

    Vegan milks could possibly be made more delicious and possibly more like actual milk with custom liposomes of optimal sizes, making liposomes is as simple as putting soy lecithin or sunflower lecithin in an ultrasonic jewelry cleaner which is amenable to
    industrial scale up, this could improve milkshakes and ice cream as well

    I have not tried it but I read adderal(tm) makes sustained studying easier, it likely heightens study quality, screening a library of amphetamines and amphetamine like compounds at mice to find those that enhance studying without activating dopamine
    neurons, so they are absent thrill and do not prompt reuse,the mice could persist and score higher at voluntary learning tasks and fMRI and possibly positron emission tomography and molecular biology could figure out how they work, there could also be an
    advertising slogan, get three hours of studying done in two, spend more time with your lover and friends

    I think 2/3 or 3/4 circle porthole doors that look like 2/3 or 3/4 of a rising sun may have pattern resonance benefits, even if they do not they look nice, especially the white ones, they could install them anywhere and installing them at schools is
    possibly beneficial

    The paranormal beings I perceive include bees as a hive mind, to benefit bees they could find the minimal amount of queen produced chemicals that keep a hive functioning, at same honey output, feeding all bee larvae with more royal jelly (there are
    already honeybee varieties that hyperproduce royal jelly) making them live longer and possibly more resistant to disease, developing a new kind of nectar and pollen rich plant with seeds so tiny they cling to bees like pollen does and falls off in flight
    spreads the plant, optimally the flower would persist even with seeds (there are peptides that effect flower petal duration), I read that duckweed has the smallest known seeds (to that person on the internet), so some of those genetic components could
    contribute to land plants, I think ferns might have smaller spores

    At inkjet and other printers paper quality can effect image resolution, lasers could flatten paper fibers of affordable normal paper through a few mechanisms, they could non thermally ablate it(like laser dental fillings) mowing it like a lawn, they
    could adjust the moisture enough to uncurve the fibers, they could use published laser tweezers that can move 3mm balls in fluid on much tinier paper fibers, or they could ultrasonically flatten it, the paper could be smoothed with a separate flying head
    from the inkjet head

    Coloring books could be reconfigured to heighten and optimize the pleasure of the swoop of the pen, utilizing quantitative measures to find the shapes that are most pleasurable, also there could be larger blank areas throughout the image design prompting
    the colorer to draw their own thing, circular areas and shapes like those at the math amusement sprouts are more optimal from a pattern resonance perspective, artists drawing on blank media is beneficial as well

    Sometimes students space out or get distracted, they could quantitatively measure the students perception of a focalized them-only speaker produced voice both during and after class, the voice could try out different phrases (ask!), tones, and pleasant
    voice characteristics that the students measure as being most good, potentially even enjoyable (acoustic guitar), likely varying the sound between events that cause just 9% of students to be attentive, sometimes though the student would hear something
    like give a thumbs up if you are glad I said Hello, the speaker would have a camera and further customize the experience to each student so they liked it so more and and more would voluntarily participate, students that do not like it at all would be
    automatically opted out after three days, this would be quantifiably measured to verify that actual learning increased

    The same individual only acoustic technology I have read about can be voluntarily placed on bike handlebars saying, or toning voluntary prompts that are quantitatively measured as making bicycle riding even more pleasant and enjoyable and the person glad
    they installed

    Coated seeds already exist, as do tree planting robots, coated seeds that also contain a multiplicity of small nitrogen fixing seeds, like clover seeds could be coated so the nitrogen fixing plant germinates a few months after the main plant like a tree,
    providing nitrogen to the plant, if there are nitrogen fixing plants that automatically propagate with runners that would be beneficial, it is possible a coated seed disc with a wider annulus of nitrogen fixing seeds works better, and as long as the
    nitrogen fixing seeds would grow they could be placed two or three seeds high at a coin sized disk made of compressed Jiffy-Pot material, drones or robots could place the disks

    I read that there is published research that says injecting rodents with the blood of schizophrenics causes death at the rodents, perhaps at lower doses they just act different, finding what those chemicals are then immunizing against them so they are at
    well person levels could reduce the symptoms and experience of schizophrenia, immunizing primates to produce much reduced values compared with well primates could be studied to find out if there is any behavioral benefit, possible longevity benefit (
    measurable at mice) and if primates taught to place an object on a slider bar that describes their mood changes, I think the slider bar can be taught if there is something like a brief animated gig at each distal area of the slider with one displaying
    glum behavior and the other displaying how a primate behaves when it finds a cache of treats, while first learning to communicate mood with the slider bar the primate gets a treat whenever it puts the object on the slider bar and, when it is given a
    bunch of treats it gets a favorite toy, and if primates like physical contact a pat on the back to reinforce that something that makes them feel good, when they report on it causes things they like even more, to teach them to adjust the slider bar when
    they are glum something like an identical version of their favorite toy is presented to them, and if they move the object towards the glum part of the slider bar they get a treat and are presented with their original intact toy, after learning to express
    their mood the well primates are then immunized to have much lower amounts of the chemicals in the blood of schizophrenics than median primates and they then report their mood, it is also beneficial to simultaneously teach the primates that the animated
    gifs represent the emotion they feel by switching the poles occasionally, positron emission tomography of primates brains and fMRI may have numerical linkage to human brain scans and equivalent or partially

    Localize dopamine antipsychotics or completely different antipsychotic drugs to just the brain scan areas that are different between well people and schizophrenics

    Antipsychotic and other drugs that change cytomorphology with kinesin or maybe actin to lengthen or shorten cytes among them neurons to reduce or even cure schizophrenia

    Do people with longer dopamine neurons have more fun and are happier than median

    A technology could be developed that provides veterinary care to free range actual non domesticated animals, drones, peptide and protein drugs 3d printed casts and the drones do radiography or other imaging, they could even do biometrics and accumulate
    medical histories (like charts) gene drive longevity wellness genes as previously described, epithalon and thymosin peptides

    There are drapable foam sheets, and there are reflective mylar-like emergency blankets, but I have not heard of a durable yet disposable reflectorized baby blanket that benefits babies, notably at the developing world, they could quantitatively measure
    babies surface temperature and a possible reduction in crying quantitatively and iterate improvements

    When people repeatedly use a chemical I read that their baseline neurotransmitter response adjusts and sometimes they prefer otherwise, I may have had this response to phenibut, it went from thrilling to fun, and I thought if I took it too often my
    baseline neurotransmitters might adjust to less than fun, people could voluntarily readjust their neurotransmitter responses to the amount they had before taking any of the neurotransmitter response baseline adjusting chemical, it is my perception I read
    that antibodies can be made that attach loosely and temporarily to other chemicals, proteins and cytostructures, an interval similar to a medically quantified success at tapering off a neurotransmitter neuron could be the duration of attachment of the
    antibody, I have read that there are antibodies that can activate a receptor or passivate a receptor, so whichever way the receptor is, from the person's perspective at a non optimal activation amount from endogenous body chemicals the gradually
    detaching antibodies can duplicate the 99th percentile of quantified successful chemical tapering, it is possible that this could be a one dose oral antigen, in an enteric coated pill with the antibodies encapsulated in micelles (which are published as
    passing the blood brain barrier) the outside of the micelles could also have membrane transport peptides attached to them to both better transport through the blood brain barrier as well as do some localization of effect, there are published maps of
    where antibodies accumulate at the brain so the outside of the micelles could, optionally have those brain area mapped antibodies attached to its surface, an online paper mentions vaccines at 17-50 milligrams per dose and,"tablets with dried vaccine
    incorporated and supplied with special coatings" are functional, another approach is to molecularly attach the micell to the neuroactive chemical, with me, phenibut, or a bunch of phenibuts with the possibility that it will migrate to the same areas as
    phenibut

    Even though I mentioned phenibut as a drug I thought about tapering off of I think the benefits have value

    People online say they think they look better in the mirror than in phone camera images, there could be an app or filter item that does the same things as an actual glass mirror and good bathroom lighting as adjustments to the image, it could have
    adjustable values to possibly intensify what might be an improvement effect, the looks better in mirror effect might just have to do with eye contact, motion (people might look better in animated gifts) and duration of gaze, if so then that painting
    style where the eyes of a portrait follows you around the room could be part of the filter effect


    [continued in next message]

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From Treon Verdery@21:1/5 to All on Fri Sep 30 10:12:58 2022
    Gene therapy at the teeth, tooth nerves and gums might be particularly easy to do and be durable for any gene therapy purpose

    The people with what is called superior autobiographical memory may have some shared genetic variation like alleles or SNPs, genes from people with superior autobiographical memory that are well and above the 90th percentile of happiness and placing
    those at mice and seeing if they remembered last years, or 2 years ago's learning of what they previously learned could find enhanced genetics of human memory beneficial to put at all humans, that is persons, that is people, as well as new gene therapies
    and drugs, notably people would get even more out of education

    I have read about using air emitting surfaces at airplanes to enhance aerodynamics with active control surfaces, I also read that flying at higher altitudes uses less fuel because there are fewer air molecules, it is just possible that air emitting
    aircraft surfaces or helicopter propellors or watercraft propellors that emit lower than ambient concentrations of air (similar but slightly different than PSI), at high enough velocities (like an air hockey table) could heighten fuel efficiency

    Some person figured out that scooters and few-person single cabin people movers (kind of like light rail cars) can increase fuel efficiency and scheduling flexibility, with computer/AI pilots it is possible humans traveling on multi person ultralight
    aircraft (as they are classed) could be more fuel efficient, and airport size and scheduling flexible, also the aircraft parts are smaller and easier/cheaper to build

    I perceive that paranormally knowledgeable, or even just paranormally educated people can arrange objects or do things that cause benefit, even benevolent benefit from what I call pattern resonance as I do not know its actual name, an AI (artificial
    intelligence), possibly a deep learning AI noting those AI that learn without precoded algorithmic specificity processing of all human actions and environment the video of a municipality, a townn and a forest dweller could use object finding and word
    recognition and quantified human occurrences over different timescales of varying orders of magnitude at deep learning to find completely new to published occurrence effect relationships at what I describe as pattern resonance, that are absent a 20th
    century mechanistic explanation, one JY described is that getting new shoes causes men to get new girlfriends or new sex partners more frequently or also more rapidly, one I am just making up is that putting a book with the title romantic success with a
    box of candy on it on top of a white electrical power supply and then eating a candy a day would increase the romantic advantage and frequency of women, testing JY's technology is likely to be more effective

    They could find the 99th percentile of pleasant psychology word: arousal with phone software and fMRI, then use those to build other technologies, like effective greetings and awards, hugs, beautiful happy people, and amusement parks and amusement park
    rides cause pleasant arousal moments in me, this could also replace negative advertising and possibly aversive material at videos, films and written media where the attention and amplitude of emotion at written or typed materials is valued, notably
    commercially valued

    The most affordable microcontroller (more capable than, but similar to a CPU) I found as the first link on a search is 23¢, at 14-20¢ to manufacture they could make a datalogger that records system diagnostics and voltage levels and frequencies with
    much more memory for the same or even less, placing this at utility meters, any device where people contest accuracy above 5$ is beneficial, 64 mb is a logged system snapshot every half second, and 64 mb is just 42/1000ths of a cent or less at a retail 1
    TB flash drive, so it could still be 14¢-23¢

    An opiate peptide, or a GABA active peptide could be molecularly attached to a sex hormone at microgram dosage amounts to preclude or treat menstrual cramps because the uterus would omit contracting and, I think, localizes concentrations of sex hormones
    at the uterus, at peptide quantities inkjet printed paper mini-squares could be 1/40th of a cent each

    Fluorinated and/or ethynylized and or peptide that localizes to the brain moietyed as well as cytomembrane passing peptide moeityized LSD and MDMA would be perhaps femtograms (LSD) or pictograms(MDMA) to 4 micrograms per dose and, at the dose form of one
    nerds(tm) candy volume would be, at 3700 Nerds per $1 1/3700th of a cent per LSD or MDMA equivalent dose

    LSD and MDMA enhanced localization moiety versions enshelled in micelles, with the micelles having cytomembrane transport peptides make the original drug molecule more affordable as well, it is possible a variety of different recreational drugs could be
    micronized causing them to be several orders of magnitude more affordable, attaching brain localization peptides, cytomembrane passing moieties, or and also harmless loose-fitting antibodies to neuron membrane surface proteins on the exterior of the
    micelle would localize the recreational drugs to the brain, the micelles could be taken orally, micelles with holes (whiffle ball) or polymer stripes that disintegrate from enzymatic effects only inside the neurons could provide a Rush feeling even if
    the dose was taken orally

    At a variety of therapeutic, recreational and better than well drugs as well as immunizations, RNA drugs and possibly gene therapy drug containing micelles with enzymatically degradable stripes, dissolving shell layers or even the published
    electromagnetically switchable and organ localizable medical gold nanoantennas could be optimized as to the velocity of onset or action, concentration of delivered drug, and chronologically custom shaped waveforms, pulse amplitude and shape at longevity
    drugs or and also recreational drugs that just keep getting perceptually higher and higher and more pleasing then stop, leaving you clear headed)

    A two chamber micelle or an "8" shaped micelle festooned with localization and cytomembrane transport moieties could have a get high (recreational drug) drug on one chronological schedule and a get sober drug or molecule disintegrating enzyme in the
    other chamber, when each of the chambers dissolves, possibly from either different enzymes or different micelle thicknesses then the high is converted to clear headedness and possibly neural healing or a return to prestimulated state, reducing a dosage
    escalation to keep getting high effect, or a maintenance dose prompting effect

    Dopamine is a neurotransmitter that does not pass the blood brain barrier, dopamine is associated with feelings of excitement and reward and pleasure, delivered to neurons with cytomembrane passing and brain area moieties or and also neuron localization
    moieties micelles containing dopamine could be variously a therapeutic drug, an antidepressant, and a recreational get high drug, this micelle full of neurotransmitters is likely also a technology at a variety of other neurotransmitters as well

    Things that make children happy, putting a wide variety of combinable faces and body forms at 3D VR headsets and giving them surface samples to touch at just 7 styles of head, 7 styles of body SA, 7 styles of limbs and 7 special effects is much more than
    39 million combinations (11 factorial) so along with the VR play testers they could have a webpage or click able ads to reach 39 million different reaction responses from children, the 99.99th percentile of most liked doll or toy shapes online would be
    3991 toy models produced in an automatic scripted way with CAD testable by 11 children in one day

    Neural network learns toy part preferences from 11 sampled children touching actual textures and seeing toy parts, a panel of 7 touchable textures like pen grip rubber, doll face rubber, stretch Armstrong fleshiness, doll face plastic, a couple
    engineering resins, microplush ultrasoft cloth, wood, as well as many others could be tested, at 11 seconds per preassembled panel of actual touchables, with measurement where two reusable music style keyboards where you press any key along its length to
    indicate how spontaneously fun it is (one keyboard) and if your mood (relative happiness) and feeling of funness went up or down (the other keyboard) when you touched it (this is similar to a slider bar test), that is tested, each child can view and
    tactilely test 411 textures (or toy parts) in four hours with two hours of each four taken out for refreshment breaks, and they can quit anytime, the 11 children testing toy parts (7 for a week that is 4525 funness and happiness measures per 2 hours of
    touching per day (11 children), or data 49,000 different data points the AI deep learning can learn from, get various 99.9th percentiles at, find the foci if there are multimodal distributions, find trends at, combining this with the website/ad data on
    the 99.99 the percentile of 39 million of preferred body forms produces new dolls and toys, and new design material trends and forms that make children happy and have fun

    The neural network toy preference dataset could even make 3D printed toys happier and more fun as well as making toys crafted by social companion robots even happier and dinner

    WiFi toys and dolls, these are likely already in development, a WiFi toy could automatically download 99th percentile funness of activity or a 99th percentile educational lesson plan (from a populous website with a rating system) when it wasn't being
    used, the cheapest WiFi chip on board I found online was 39¢, it could voice material, use the cloud and AI to do smarter things and sing songs from your CPU speaker (like Alexa echo dot)

    Plywood and particle board have a glue component, I think I have seen particle board with sparser core density, but I am not aware of plywood with foamed glue, requiring less glue, foaming glue at plywood and particle board would use less glue, permit
    cheaper fillers like clay or gypsum or even microgravel and make building materials more affordable, also, just like railroad ties with eentsy metal end caps on them plywood or particle board with mineral or concrete infused edges might be more durable
    and have greater dimensional stability and flexion strength at construction

    Babies like breasts, and humans like food, but humans like sweetened food more, sweetness peptides are published that are 200,000 times sweeter than sugar, to encourage babies that have trouble latching on, and for mothers that might notice their babies
    are happier with a sweeter treat, orally available sweetness peptides at a maternal dose of 1.5-3 micrograms a day would sweeten breastmilk, they could attach a beneficial to babies, children, and adults peptide, possibly a growth peptide, epithalon,
    thymosin, a pineal peptide, a tissue healing peptide or and also a nootropic, they could test the sweetness peptide combination or concatenated peptide on rodents, monkeys, and farm animals first, it could even get veterinary use first and the data that
    the combo peptide was bodyweight harmless and otherwise harmless to analogous child and adult farm animals throughout their lifetime, also noting any benefits, thymosin and epithalon, I read at a non peer reviewed description reduces infectious disease,
    thymosin, one of several thymus peptides thymosin alpha 1, is published at one study in a peer reviewed journal as being prophylactic against infection, making the copeptide (or on string peptide) cyclized with D amino acids could make it so it actually
    beneficially reaches the baby, peptides can be made into a slurry with tasteproof enteric coating formulas and put in gummy one a day pleasant tasting chewable gems, if infection preventing, combined with milk sweetening peptides are harmless and
    beneficial to babies they could also be placed at 1/10-1/40th of a cent a dose inkjet printed paper minidots and be affordable globally

    Increasing the potency per dose of a breast milk sweetening infection preventing combination peptide could possibly go with attaching it to a galactogen (causes greater breast milk supply), there are drug galactogens as well as galactogen chemicals in
    fenugreek, microgram doses, molecularly attached to the anti infection peptide could localize the anti infection peptide

    It is possible that a continent spanning rescue assistance radio could fit in the size of a kefob a long monofilament infused with soluble ions is infused with salt or other things that make ions to make a long conductive antenna (saltwater antennas are
    published) and is solar powered, a 6 farad capacitor is 50¢ on alibaba.com, and, I think, raise a 200 milliwatt current trickling in from the photovoltaic to several watts, if 5 watts can be achieved then that is ham radio wattage and that crosses
    continents, and sometimes the world, as the multifarad capacitor multiwatt pulse is very short something like a one millisecond data chirp, possibly encoding bank balance and words that say rescue will be financially remunerated, that can be received,
    there are already ham radio operators that scan rescue activity and are likely to willingly pass on rescue information and multi-ham triangulation data at a website, the user optimally flings part of the key fob over a tree or otherwise elevates the
    antenna, perhaps semiconductors could handle the data chirp, or, I read about non silicon high wattage other element semicondors, alternatively a very widely spaced data chirp could have just a few bigger transistors and send just a few bits of the data
    per second (tinyURL) and the ham radio accumulates a full reception

    A money sending site that asks the rescuer numerous identification questions could be beneficial at key fob radio rescue



    Longevity technology, Previously described is using radio labelling and tomography to make a map of all the tissues and organs that it is active at then make drug variants that localize and concentrate those tissues and organs, then measure the longevity
    increase from that drug as well as the longevity increase from that localized drug coadministered with epithalon, doing this with rapamycin and other longevity drugs as well is likely to be a beneficial source of new longevity drugs

    Epithalon has a plasma half life, if that is less than 24 hours then making a version with 24 hour or longer plasma half life could be tested for even greater longevity and disease prevention effects,this could also be done with other longevity drugs,
    alternatively as epithalon is related to a pineal peptide, time of day or pulsatile dosing might be more effective

    connecting the circulatory system of old and young fish that are fairly sizeable could have the same longevizing effect as connecting the circulatory systems of a young rat and an old rat, if so, they could find the chemical difference and then
    administer those chemicals to mice to find out if they live longer as a source of new human longevity drugs, this could also be done with lizards and amphibians

    At the young and old mice that have their circulatory systems connected, causing the old mouse to have greater longevity they could try partial mice, like mostly no body (extra head), mostly no brain, as well as versions with various organs removed, that
    would localize longevity effects to particular organs, noting the size for surgery this might work better with farm animals once those animals have demonstrated a longevity effect from a young-old pairing

    This is unlikely, and I am unsure how to do it besides drugging the mother, but having the infant mice nurse for three or four times as long, then finding out if the infant mice live longer could possibly find a longevity effect and be easily voluntarily
    applicable at humans, the mice should live at cognitively rich environments, they could also look for behavioral effects at the same time

    Enunchs live longer, do ovariectomized mice or rats or farm animals live longer, they could try organisms ovariectomized both are and post puberty, this could result in new receptor blocking drugs that increase longevity

    "I like ike" was a slogan, I like dyke, I like bike, I like trike

    Reusable sheets could be semipermeable and have a washable pad under, or a part of them to get rid of the wet spot from sex

    Are there any neurotransmitters or brain trends that actually increase over 30, if there are then mild doses of mild receptor blockers to those age trending neurotransmitters feel and act younger and be physiologically beneficial as well

    The elastic edging on fitted sheets could have light blue color on just one side so people could tell which way was up

    Topical epithalon may be absorbed sufficiently to be longevizing, antiperspirants might reach billions, there are some peptide based antiperspirants available online, "CH3 Pentapeptide-3 and Acetyl Hexapeptide-3 (also called Argireline), which are both
    Botox™-like peptides", "Studies on argireline for anti-aging have found that a 10% concentration reduced wrinkles by 30% over 30 days", Klima hyper-dri these could also contain epithalon as a longevity technology GSK

    Opsonization Gunks up things like some protein drugs 10W40 like molecule (10W40 motor oil uncoils at different temperatures) roll coats a drug, then only unrolls in the different enviroment or pH of the actual intracyte fluid space, making the drug
    available to the cyte, the surface of the 10W40 thing is engineered to be opsonization (gunk) resistant, this could be used at longevity technologies as well as other drugs, "a decrease in pH converts hemagglutinin, a protein in the capsid of the
    influenza virus, from an anionic hydrophilic coil to a hydrophobic helical conformation" (10W40)

    I just read that cyclizing peptides, notably with the option of putting lipophilic groups on it to facilitate membrane passage improves oral absorption, a 3 or 4 unit cyclic repeat of epithalon could have both moiety adjustable localization and greater
    oral availability, also, it is possible that enzymatically degradable linker amino acid sequences that respond only to enzymes in the intracytoplasmic space

    Topical rapamycin at the 60% mouse longevity increase dose, or possibly higher, the dermis looking 28 at 70 or better, also a reduction in skin cancer could come from rapamycin or also epithalon like liposomes in sunscreen

    The equivalent of human supercentenarians as pets and possibly farm animals could be found from asking veterinarians, then tissue samples could be available, one possible thing to look at are things like younger than predicted organs and joints at the
    supercentaniarian pets, also pets are commercially clonable, laboratory animal groups for longevity research are producible this way

    A moiety that concentrates an analgesic like naproxen at cartilage might get rid of some arthritis symptoms, there is a publication online that says avidin concentrates at cartilage, so attaching naproxen to avidin might work, they could also screen a
    library of chemicals to find others that concentrate at cartilage

    I read that glucosamine is as effective as celebrex at treating joint discomfort, gene therapy to produce glucosamine endogenously at people may be beneficial, perhaps localization protein avidin attached to glucosamine would be even more effective

    There is a statue near where I live with a circle of lights, someone broke all the lights, I think a new kind of light fixture would be very hard to break: 3 50k hour LED lights connected so that when one stopped working the next one would turn on, then
    a several inch glass tube, lens shaped to bring the light to the surface, if people broke the surface they could just clean it and pour acrylic resin on it to repair it

    Ideas that are new to me thought of while reading odditycentral.com

    Aerogels are, like,96-99% air and can be made from gelatin, could aerogel particles soaked with drugs, possibly be the right size (like 2.5pm) to get deep into the lungs and be a beneficial protein asthma drug, GSK

    Water weebles, weebles are a toy with a base weight so they always stand upright, a bathtub or pool toy that is like an air filled tube with a base weight could have Lego dimples on it, build your own floating castle or oil rig in the pool, could also be
    used with Lego's that always float

    To me, car airbags look like circular pillows, perhaps if they were contoured (I am reminded of the ergonomic contouring of seats) they would be safer and more pleasant to experience

    Ferocious animal blocker, if a ferocious animal comes near then a harmless laser eye dazzler could confuse it and temporarily block its sight of you, the improvement is that a camera and computer find the ferocious animal, then steer the laser beam to
    always be on the ferocious animals eyes regardless of how it moves, how the person moves, or even if the person turns their back and runs away (if the person has one on the back as well as front of their belt

    Computer controlled self driving vehicles create the opportunity for new kinds of tires with half or double length stopping distance based on tread composition, also it has likely been thought of but a self driving vehicle could also see the road (wet/
    dry/concrete/asphalt/gravel) and compute customized stopping and acceleration, heightening safety

    Declawing animals gets mixed reviews in 2019, it is possible lasers, like cofocalized lasers could zap the claw or nail bed so it grows thousands or tens of thousands of little keratin frondlets, these feathery hairlike frondlets would be absent harm and
    possibly, like laser eye surgery, be sensationless to produce, humans that frequently manually stimulate vaginas like lesbians might have their fingernails filamentized to assist in partner well being

    Better lyophilization and freeze drying, focused acoustic likely cofocalized pulses could be aimed at material being freeze dried to push water and water vapor out to the surface it is possible a ripple pattern or expanding sphere pattern could be used,
    this could also benefit the quality and kinds of freeze dried vegetables

    Combo charity oaks support charity marketing, marketers could test whether combining charities causes more donations like "cure cancer ..and save a child" or "give to MIT and get a robot for a science camp girl" this would provide the concreteness of an
    actual thing with a general charity

    I have seen art marker pens that turn transparent when another bleaching or other chemistry pen is drawn over them but I have not seen this with watercolors or acrylic paints, I think it is possible

    A chinese person got zapped with a rock and stopped visibly aging after brain surgery, they could find what area of the brain that is and find out if procedures or drugs localized to that part of the brain longevize or cause youthful appearance at those
    over 14,"doctors discovered a blood clot in his brain and performed emergency surgery to remove it. The boy recovered well and his life seemed normal for a few years after that, but at age 9 his family noticed that Zhu looked undeveloped compared to
    other boys his age."

    White lasers could be combined with other lasers to make beautiful pastel art, lasarium, building surface and various art

    Room as push around gel beads or gummy art erasers to clean stains, the human dumps some gel beads or art eraser beads then the roomba herds one or more of the beads to where the stairs then rolls it back and forth, or rubs it back and forth then herds
    the beads back to the corner

    Feeding dairy cattle they could breed a kind of hay full of beneficial probiotics that support beneficial probiotics at the cow, GMO hay that makes the four amino acid longevity peptide epithalon at amounts functional at an oral dosage could cause longer
    milk giving lifespan

    A study of magnesium amino acids (Mg threonate is one but there are 23) could find a harmless or beneficial muscle relaxant, just magnesium alone is described, along with medical uses people could take this before getting a massage, then rate which of
    the 23 magnesium variants improved the massage the most

    Fat and oil substitute, thinking of detergent molecules with a hydrophilic distal part and a hydrophobic distal part a molecule with two distal carboxylated alkanes with a long carbohydrate linear molecule between them could have an oil taste or effect
    at some fraction of the calories, laureate-sugar(or mini starch polymer)-laureate might be one, they could find out if making the distal alkanes omega 3 fatty acids produced wellness benefits

    There is a thing where AI generated squiggles generate more brain activity than most other things, it is possible there is an AI generated squiggle quantitatively measured as heightening productivity (possibly office productivity), they could make this a
    corporate art form as well as part of motivational posters

    I think genetically engineering crows, ravens, all the corvids, and African grey rock doves (pigeons), sparrows, and robins to be all white is beneficial, crows and all the corvids could also be genetically engineered to have sweet voices, engineering
    these birds to make all their own vitamins simultaneously is also beneficial, using gene drive to engineer birds is also beneficial

    A pill that makes things feel better and removes distress, possibly also a high feeling that does not lose potency or utilize escalating dosages to keep working or get high, I have not tried benzodiazepenes but I perceive they get rid of anxiety and make
    people feel good, they work on GABA receptors, a molecule that attaches a GABA activator group to an enzymatically degradable linker that only degrades while the person is asleep, optimally non-dream sleep, and the linker passivated a GABA neuron
    antagonist molecule causes GABA to go up while awake and down while dreamlessly asleep with the net effect being an absence of tolerance effects as the tolerance to the GABA antagonist supports the continued function of the GABA activator while awake,the
    thing is they would have to work on the same physically located neurons, so something like alprazolam-dreamless linker-methoxyAlprazolam is a possible molecule (methoxycaffeine is a sedative), one possibility for activating the GABA antagonist only when
    dreamlessly asleep is to have the molecule like alprazolam attached to a photo activator that only activates when light of a nonvisible frequency strikes it then illuminate the persons face when the computer notices they are at dreamless sleep, this
    could work with other drugs as well

    I just read that human neutrophils a type of white BC live just 8 hours, as a longevity technology they could screen a vast library of chemicals, including microfluidic automatically combinatorially generated RNA and peptides to find things that increase
    their lifespan, perhaps even doubling it, successes from that library screening could then be tested on mice as longevity drugs, this might also assist with maintaining quality of stored blood plasma, it is even possible that neutrophils that live twice
    as long cause people to be much less susceptible to disease, if so a 1/10 of a cent inkjet printed paper dose of a neutrophils longevity drug could save many lives and many children's lives

    Using screening of libraries of chemicals at neutrophils it is possible millions of variations on the salicylate molecule could be tried as it makes yeast live 400% longer

    I just read porous concrete is beneficial in reducing runoff, perhaps particles of something like easy dissolve magic rocks or hollow easy dissolve capsules could be a cheap way to make pourable porous cement

    Spray on dresses and cling decals could be used to make evening wear and wedding dresses cheaper than couture fashions that fit even better

    Hiking shoes with the words Look up, look around, right side up to the wearer could be measured to see if they actually cause hikers to look up from the trail

    Similarly a jacket clip on the collar or zipper area could unobtrusively change color or very gently light up if the camera in it noticed you were gazing at the ground a lot, skiing version also possible

    In Japan one gourmet/status grape can be a few hundred dollars, it is possible laser engraving the stems, on the vine or off it could adjust the flavor making even more optimal flavor possible, at general agriculture a laser engraver and camera, affixed
    to the ground or flying like a drone could edit stems to optimize ripening, accellerating or delaying ripening to produce optimal flavor and harvest amount as well as benefitting flavor much more affordably, notably CD player lasers can pop rubber

    This one is a little iffy, there is a thing called a Tesla valve that used convoluted passages next to a main passage to make it so fluid flow like air, or possible water tend to flow in only one direction, it is possible minipatterning of machine and
    industrial seals could keep more dirt away from the bearings, causing greater lifetime, there might be applicability to windshield wipers as well

    I read that attaching a magnet to an oil pan grabs particulates and the engine runs longer, it is possible machine seals with a halbach array, which has a strong magnetic field on one side only, placed on the exterior of the seal, possibly a Tesla valve
    seal, would accumulate magnetic gunk causing greater bearing lifetime

    Saliva tests are used as diagnostics, it is plausible these could be four to ten times more effective if antibody containing fluid, candy, or gum were chewed or swished in the mouth, where the antibodies have high recognizability to the actual test (
    which might be antibodies to reacted, that is glommed antibodies, this could make a wider range of things testable with saliva,also the higher avidity of the second antibody for the detector increases sesitivity

    Bubble wrap condoms, condoms with something like the bubbles of bubble wrap along the shaft area could be measured to see if they quantitatively increased women's pleasure from both texture and added girth

    A wide variety of medical implants exist, positive, negative or neutral charge is published as keeping protein clotting from occurring, it is possible these same materials at food tubing, spray nozzles of all kinds including spray paint and container
    taps, possibly even the straws and interiors of reusable sporty drink containers. Camelbacks(tm), Tupperware type containers and other things


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