• Gene logic

    From Treon Verdery@21:1/5 to All on Tue Oct 4 01:16:03 2022
    possible that without antibodies, this would cause autophagy at virus inected cytes from their being at 30th percentile or less of wellness quantifications, the incidental antiviral effect could be beneficial to both the person, and even possibly reduce
    the amount of viruses circulating at the population. The 30th percentile of wellness autophagy technology could be a nonimmunosystem new to me approach that kind of incidentally removes virus infected, oncocyte, and even possibly, fiberous nonutility
    tissue, which might be replaced with weller cytes. It is kind of like a new to me, multipurpose, new (30th percentile quantified effect at any nonoptimality) kind of senolytic, with different criteria than various intracyte deleterious products like
    interleukins;



    the versionbs of these technologies or others that create longevity, wellness, and healthspan beneficial new versions of autophagyor germline enhancement or optimization





    Longevity technology: an antiglycation mechanism could be found at some animals then tested at mice anfd humans to see if it increased longevity, healthspan, and wellness, also, gene variations at humans like SNPs could be correlated with wellness and
    absence of or reduced glycation at humans, and then causality measured with mouse studies to find beneficial genes for human gene enhancement or also optimization; notably though I perceive plants also do the nonpreferred glycation of proteins, so
    anything at plants that is produced at cytes that reduces glycation could be tested at the mammalian genome to find out if it benefits longevity, wellness, and healthspan, notably the 40,000 year old King’s holly, the 10,000 year old creosote bush, and
    the 4k year old conifer might each have a different plant genetics of antiglycation that benefits their longevity that could be tested at mice and humans.



    When a person gets gene therapy, they might like having a way to utilize their previous genome at some or even all their cytes: backup with gene therapy: crispr/cas9 appends the new genome to the previous genome, puts a start codon (or start codon group)
    imaginably at a sticks-out circly pouf on the nucleotide double lane topology, the body ignores the first, previous, genome, which might even have some stop codons crispr/cas9ed into it at easily recognized locations (sort of like restriction enzymes say
    “thing here” perhaps stop codons could be placed at the previous genome anytime a CCCCC occured, so if editing it out it would be near errorless to utilize the previous genome, if the utilizer felt like it.



    I have not read about any siRNA longevity molecules, It is possible these are possible, and that siRNA that heighten AMPK and decrease mTOR (or another 60% greater mouse longevity mTOR drug, that works on just mTOR1 rather than mTOR1 and mTOR2), siRNA
    might be even better at reaching the CNS through the blood brain barrier as their AMU is less than some other nucleotides







    I perveive there might be a million or more actin lanes per cyte, at 70 trillion cytes, that could be like a math iteration structure with a really large number of math areas to model, algorithmize, and generate, something like interpretations about
    things as compared with, and possibly as a beneficial resource to the brain and CNS; Like what if the 70 trillion cytes with actin paths simulated various effects of various possible things, and communicated the modelling results with a one thing one
    meaning language;



    um, I perceive how DNA per cyte has lots more data space, it is just that actin paths also have lots of functional movement, geometry, spatial accessibility…



    It likely already exists, but is there a CRISPR/cas9 automatic gene sequence linker? I perceive different lengths of DNA have different easiness of transfection like 3/4 a decade ago (2011), but the perception I have of of CRISPR/cas9 is that they have
    figured out how to make. transfer, and activate things with out about 20,000 genes with simultaneous high velocity, high accuracy, and high editing sucess (transfection); complementing that, perhaps at a variety of sizes, could be something that is
    effective at attaching one sequence to another, at a functional place and physical form, (imaginably, histonated, less histonated, a loopy part available because of a mitosis, translation as well as transcription event, meiosis, or some new thing that is
    new to me)



    so, one approach is to find the easiest histones on earth; some mammal has histones with really long, super editable, physical like-new preservationess above other mammalian histones, really available DNA; completely making a synthetic sequence of that,
    then making if even more genetic engineering friendly, then placing it at a variety of mammals, likely including humans, could benefit DNA transcript fidelity, DNA preservation, translation velocity at organisms, like humans, as well as heightening
    beneficial, functional, engineering friendly genetic editing, modification and genetic engineering;



    Also, besides unlooping things, and actually I have no idea what they do, but I perceive DNA is unusually accessible during translation, mitosis, meiosis, and possibly some kind of “make this” thing that something at the nucleus says, like imaginably,
    if something says “make ribosomes” perhaps hundreds of ribosome making DNA locations get sequentially availabilized rather than just like one, over and over again; so, it seems possible they have tried loading up a well human cyte with a numerous
    quantity of things to translate at DNA, so they could unspool a bunch of DNA, efficiently, and edit it;



    Along with making like a big list of DNA access producing translation instructions, they might have some amazing thing like a DNA translation smoothified new to me histone that makes DNA completely available to editing (like crispr cas9 or more advanced)
    while being a place to have a lot of DNA stay linear, functional, well, effective, and immediately ok to utilize without repairs; the smoothified histone could even be nifty at some ethynilization methylization optionalizing, gene modification now able
    to be unaffected from methylization and ethynilization molecular topology effect; a smoothified histone like an inspection and upgrade access area of an airplane;



    Is there an artificial intelligence thing where if people, or AIs share the technology the sharers accumulate greater prosperity; it is possible AI APIs



    Longevity technology: finding human gene variants that predict responsiveness to different longevity drugs would be beneficial. Rapamycin and a rapalog each are published at 60% longevity increase, my perception is that that math functions describe a
    medianized response, so noting half of all persons are above median, perhaps a greater than 60% rapamycin response could be predicted, and a gene therapy or a coadministered gene product upregulating drug might be able to cause a 99th percentile
    rapamycin response.



    Squiggles developed with AI deep learning have been published that cause primate brains to produce more activity than views of faces and nature, it is possible that new squiggles developed with deep learning AI could cause greater amounts of response
    than the beauty responding areas of the human brain, and that when humans view these squiggles people describe them as attractive, appealing, and beautiful. I am not aware of research on deep AI generated squiggles that are beauty experieince activating
    above that of nature and human faces and form that are three dimesnional or that vary gradually. Among many beneficial uses of these squiggles could be decorating architecture, decorating energy producing utility plants (among them wind, photovoltaic,
    nuclear, chemical), hairstyles, and notably anything with above median utility and during the year 2019 less than median aesthetic impression; trash dumpsters, parking facilities, some public transit, medical appliances, anything on a list of survey
    generated “could look better” things at public and private spaces.



    It is possible that things that are already aesthetically beneficial like plants, landscapes, nature, aesthetically appealing humans, could have versions and variations of deep AI developed beauty squiggles, and that actual spaces could be quantified as
    to their beauty response as well as images duplicated. Also, automated mechanisms or also robots that clean and arrange dwelling spaces could arrange items that humans view and utilize to be simultaneously highly available and, with beauty squiggle
    technology, arranged at ways that cause higher subjective well being increasing beauty response than the person doing their own arranging. People could of course do their own arranging, they might more often appreciate deep AI guided arrangeements of
    things.



    Aesthetically mild to beneficial things like computer interfaces and printed text, could generate a beauty response while being combined with other deep AI developed squiggles that simultaneously increase comprehension and retention to create beautiful
    and cognitively enhanced interfaces and text; I favor a computer interface and text interface that causes heightened sense of well being (the psychometric: subjective well being increase from experiencing beauty), the “nice space” architecture effect,
    the “startlingly gorgeous” art object response, and even the human reponse to human female beauty response at persons with any form of human sex chromosomes occuring at 98% or more of people;



    There are no top of page results on a search of “chemical vapor deposition metallurgy” so these are some chemical vapor deposition metallurgy technologies. I read that 3 nanometer silicon features are produced at integrated circuit technology,
    noting that arrays of atoms can have much more than an anisotropy or two at (25 atoms per feature, one to 20something billion features per IC, ) a trillion deposited atoms, that suggests that rather than a 3 nanometer feature size a 1 nanometer atom
    group feature size could be produced, and that the dots could be customizably amorphous, crystalline, variations of crystalline or other forms.



    rather than an integrated circuit phototemplate it is possible a UV laser could produce a regular array of dots or shapes at a photoresist with diffraction grating technology, switching between a few, or even a few hundred different atom location
    preferentialization areas could produce a wide range of material characteristics;



    thoughts on the size of chemical vapor deposition metallurgy part sizes: MEMs technology could also be a guide, with thickest chemical vapor deposition metallurgy being some higher of power of two than the 24 hour thickest MEMs object production cycle,
    it could be higher, if manufacturing time equivalence is considered (a company orders parts for delivery every month, giving as much as 1 month photolithography growth or possibly MEMs thickness build up), if something like UV lasers with a diffraction
    grating can be adapted to modify the shape of a growing single crystal of tungsten, like those used at some airplane turbines, then that could be a metallurgical chemical vapor deposition object size guide (although perhaps not, as I think they might
    pull those out of a melt)



    Other ways to make features of less than 1 nanometer: It is possible that one photon, even at one frequency, from a laser, could have variable absorption likeliness based on grouping and entangling (linking) photon spins. At New Scientist magazine I
    read about a quantum camera, where a beam of quantum entangled photons met a figurine, and the other group of photons the first photons were entangled (linked) with made an imnage on a camera chip, the shape of the figurine caused the figurine to be
    imaged on the chip from varied photon energy availability based on photon spin, there was an absence of an optical path between figurine and camera chip; Notably, large numbers (thousands) of photons have been quantum entangled together, and it is
    possible that adjusting the spin effects on each of the 1000 photons separately could produce 1000 gradations of either absorbability at the figurine or electrical charge effect at the imaging chip. The same technology with 16 quantum entangled photons
    making the chemical vapor deposition metallurgy optical guide could have 256 levels of possible charge variation and atom attraction/deposition/enarrayment, or also likeliness of causing a deposition; so although the physics seems iffy to me, there might
    be a locational effect beyond light wavelength, or at least an automatic 16 bit halftone effect, possibly per each 1 nanometer sized dot, possible.



    I read about the kind of thing that might be a new metallurgical effect at chemical vapor deposition metallurgy, https://news.wisc.edu/bending-the-rules-a-revolutionary-new-way-for-metals-to-be-malleable/ a new kind of bendability based on amorphous
    shear bands,



    Isotope effect technology that benefits integrated circuit fabrication technologies, I read that, “The whole wafer is then subjected to UV radiation, allowing the pattern mask to be transferred to the organic layer. The radiation either strengthens the
    photoresist or weakens it. The uncovered oxide on the exposed photoresist is removed using Hydrochloric acid. The remaining photoresist is removed using hot Sulphuric acid and the resultant is an oxide pattern on the substrate, which is used as a mask.”
    Noting HCl and H2SO4 are used at making integrated circuits, it is possible that making HCl that has only 34 amu CL or 35 AMU Cl, or just one of what I think might be 8 different stable Sulfur isotopes could change etch characteristics and perhaps one
    of these 9 variations has quantifiable benefit to making better integrated circuits and MEMs things; I do not know why deuterated, slower moving etchants would be more functional, although they might be similar to etching at a lower temperature.

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