• Enhancing Peaceful Traits in Species (2/2)

    From Kay Lie@21:1/5 to All on Sun Jul 16 06:51:37 2023
    [continued from previous message]

    Similarly, marmosets could be bread for unchanged testosterone and adrenaline levels, but 99th percentile of minimal aggression and median or higher mating frequency; then the peaceful genetic difference at peaceful marmosets found and tested as a
    peacefulness gene therapy at mice. Human volunteers then receive, first, epigenetic drugs of peacefulness, then noting that is non deleterious, gene therapy of peacefulness; Interstingly it may be possibe to attract volunteers at the human population
    with nontestosterone nonadrenaline physical aggressiveness withmoney; literally paying people some amount to get a one-time epigenetic modifier drug or gene therapy if they are at 50th percentile of physical agressiveness genetics; Philanthropists could
    promote this drug therapy at the developing world. One country at the developing world in the 20th century had 70% incidence of domestic partner violence; perhaps those people, for $30, at 2020 a month’s cash intake, would voluntarily modify their
    epignetics or genetics (gene therapy), reversibly, to be below the median at actual measured physical aggressiveness;

    During the 20th century some people disobeyed laws against violent behavior, were apprehended by agents of the government, and experienced some sort of penalty. I perceive that some fraction or percentage of the people that received the penalty feel
    their agressive actions should have been avoided. These people can be reached with philanthropic adverising, and they, and their physiological children, can receive anti-physical agression epigenetic drugs and gene therapy from philanthropists.
    Previous notes describe how do gene therapy for 1/10 of 1 cent with a pill, and it is similar with epigenetic modification. The philanthropists would do well to combine the anti-physical aggression epigenetic or also genetic treatment or pill with
    separately assembled “top 11” things that people most want. Like theoretically, many people would like to be more attractive, more popular, wealthier, healthier, richer, so those epignetics (some described as: sucesstropics at my notes) and genetics
    would be coadministered with the anti-physical agressiveness gene and epigenetic modifying drugs.

    https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005416 Is a journal artile at PLOS Genetics that traces 34ish different possible agression genes from flatworms to mice (and thus likely humans) at Of Fighting Flies, Mice, and Men:
    Are Some of the Molecular and Neuronal Mechanisms of Aggression… • Published: August 27, 2015
    https://doi.org/10.1371/journal.pgen.1005416


    Human (pro) peacefulness gene “The fierce [mouse] mutant was fully rescued with a genomic clone that covered the human NR2E1 gene”(what alleles SNPs, and epigenetics of this do what?
    NR2E1 effects mouse brain size, so may be a g (like IQ) gene at various aleele SNP forms; gene duplicates or better promoters or other gene amplfiers could be tested at NR2E1 at mice and marmosets to see if these have increased cognitive ability or also
    decreased agression, with median or higher mating frequency

    The NR2E1 paper also mentions the hypothalamus, downregulaution/surgery may heighten cognition, but decrease sex drive; combination pill: paleness bremelanotide increases sex drive while GABA and opiate and glumate blockade at hypothalamus utilizing CPP
    decrease agression and, potentially increase g, attaching moity or making pehnylethylamine distal on a long peptide that blocks it’s ability to pass the blood brain barrier could be an appetite supressant; Modifying the hypothalmus non-dominant
    hemisphere with ablation surgery caused “Increase in the fluency in semantic contexts, increase of rapidity of visual image formation and of coordinative perception processes, positive modifications in the scope of some personality dimensions (poise,
    openness, self-criticism), decreased colour perception, [greater appetite]; so the CPP anti-hypothalamus drug is likely a peaceful nootropic; it’s beneficial to make the paleness bremelanotide dose high enough to put person at 80th percentile of sex-
    partner-gaining behavior measured over 1 year of use, and 99th percentile of frequency of voluntary sexual activity.

    peptide tail taar receptors as euphoric nootropic that is apettite supressant like PEA

    Make a new ubiquitous yeast, atospheric dwelling and rainin distributed cloud bacteria, cloud yeast: effect flatworms and roundworms and more complex organisms, these yeast and bacteria make antiagression epigenetic and gene therapy; ubiquitous; Gene ray;
    antigens coded to be produced as well that cause nondeleterious upregulation of peacefulness Tll NR2E1 genes across many species; nondeleterious upregulation of NR2E1 causes peacefulness at humans

    A very simple way to find new cognitive enhancement (g like IQ) genes; this paper https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005416# • Published: August 27, 2015
    https://doi.org/10.1371/journal.pgen.1005416
    mentions 400 genes with a cognitive-nonoptimality variant, that suggests that among median or higher cognitive ability mice or marmosets or people with median or higher numbrs of progeny there could be multiple alleles/SNPs for these four hundred genes;
    Mathematically linking proxies of heightened measurable cognitive ability, such as professional degrees, SAT/GRE scores, and even noting europe, IQ tests used for emplyment, and full genomes at electronic medical records to the most cognitively optimal
    human allele variant for each of these 300 genes could be found, RNA and peptide drugs produced, and human volunteers could be administered four gene up(down)regulators simultaneously in a multiplex matrix experiment. 800 humans provides a p value of .
    05, 8 humans per four coadministered drugs per person; (all 400 potentially cognitive beneficial gene variation RNA and peptide drug workalikes tested). Initial cognitive and personality testing precedes medication, then Drugs could be administered for
    14 days prior to the repeat of the cognition and personality tests. The database with the 400 cognitive adressing genes is 2020 OMIM: This search in Online Mendelian Inheritance in Man (OMIM) [122] … there are more than 400 genes that cause
    intellectual disability [123] and relatively few are associated with increased aggression and some are associated with pleasant behavior [124–126]. Almost half of the proteins encoded by these disease genes are connected into a single network based on
    STRING analysis (Fig 2 and S1 Table) [127]. Not all of the interactions represent direct protein—protein interactions, but many of them do”

    Then after they find out which human gene SNPs and alleles most heighten human cognition out of the 400 tested they can combine these in sets of 8 at mice, so if 80 of the 400 genes have a cognitive enhancement varient, then just 10 groups of 8 mice
    receiving gene therapy is 80 mice. Then, the cognition enhancement genes can be further characterized and combined to produce rats and marmosets with all (and a germline from birth group)

    .5b cognition MMPI for rats and marmosets; 180 tasks the smartest rats and marmosets, perhaps the published rat equivalent of the “doogie NRB2 mouse)” and the “doogie marmoset”, and 11 year old 99.9th percentile human do most notably more
    effectively than their peers (press next color light bar in sequence; other published cognition tests) winnows, like 40k MMPI questions become a few hundred, forms a shorter inventory of 20 tasks that the 400/allele upside test rats and marmosets can
    work on;


    Getting new cognition drugs and gene therapies out of screening the OMIM database 400/allele-upside gene versions, noting 80 out of the 400 have previously been found to have alleles/SNPs cognitively beneficial at mice goes with 16 Marmosets receiving a
    new RNA peptide weekly, a startling one RNA drug/One marmoset protocol for five weeks. Then with the top 10% (8 drugs out of 80), testing those 8 drugs on 16 marmosets, for a sequential week each, to get a possible p<.01 value from utilizing all 16
    marmosets on one drug. The entire process can be repeated one to gain staistical strength or find the 16 top drugs in 26 weeks, that is 6 months.

    I think people naturally want their children’s lives to be even better tahn their own.

    When they think about that, they can value their children being more intelligent than they are, being happier than they are, being more Light Triad (psychometric than they are) and being longer lived and weller than they are, as well as being better
    parents than they are, having even better sex than they have, having software and trustfunds that do that benefits both parents and children
    Trustfund components
    software components


    It is beneficial to produce a nontestosterone, nonadrenaline basis of peaceful behavior epigentic therapy as a plant, a vegetative organism that not only humans, but a variety of other species could spontaneously eat and become more peaceful. This,
    noting Dave Peace’ http://www.hedweb.org Abolitionist Manifesto. The n (number) of what are called weed plants that together reach 99.9% of all of earth’s surface, might be 20-200 different plants; modifying each and all of these to produce anti-
    physical aggression epigenetic modifer peptides and gene therapies, as well as immediate action tail nestling peptides causes reduced agression amongst all species that ingest them; sweetness peptides would be made a part of the genetic engineering of
    the weed plants, (notably, DNA/gene earliest phenotype and genotype form non-testosterone aggression is decreased, one version might be from insect nonagression, Also doing that same: earliest occurence of geotype and phenotype of nontestosterone
    nonadrenaline agression genetic research on: reptiles, amphibians, sharks, the most genes shared with all vertebrates that has a CNS (central nervous system) organism, octopi, lungfish, shellfish (limpets etc.), shrimp, lobsters, krill,fish and kelp,
    The internet says worms, planaria, and c elegans show agression to each other; tlx, atro atn2 tll gug,


    Neural network, deep learning AI pattern resonance measurement: Have variously 11 exterior color, white interior vases function like aquaria and have 18 fish (p<.01) pr vase; have the software, similar to published mouse watching software, record
    behavior and longevity of the clonal fish; Have the same experiment, in a public place such as a hospital lobby where people see the 11 colored vases; Look for data trends, have the deep learning AI suggest which two colors combined would cause the
    highest deviation from predicted chance. (Let’s say White and Blue fish lived longest, then combine white and blue vertical stripe pattern at next construction for measurement; similarly if Blah_color_1, and Blah_color_2, were least effecting of
    anything, combine them as vertical stripes at another vase to see if it’s possible to get a response that is numerically “egregiously” median with very high z score (normal distribution bump narrowness) above probability;
    The software finding colors with outside probability IT/IL pattern effects then testing them at a variety of vase paint shape forms (Single large circle of color on white or other color background, ) with the forms generated by genetic algorithm, finds
    existing and new IT/IL pattern forms, and the well being of the fish suggest their effect.

    This can also be done with fish in 26 capital English Letter vases, plus Angstrom, and the numbers 1-18. 44 vases;

    I would not expect the effect to be as strong with human observed 96 well plates, but at 96 well plates and zebrafish, each plate can screen 8 graphical (Verical stripes, large circle on white background) forms at 11 colors, and 18 plates would make up a
    full observation set. Although unlikely to work, A human directly drawing colors, shapes, and numbers on 96 well plates is possible, cheap, and rapid.

    This technique can also be used with nonfish, perhaps rasing c elegans in inkjet printed color 700 different color vases or also 96 well plates will find deep neural network findable, concentratable, and amplifiable pattern resonance IT/IL effects. from
    both the human originated and the genetic algorithm generated forms. Genetic algorithms finding variants on English Alphabet letter shapes could be tested at vases and 96 well plates.

    Pattern resonance characterization vases are likely to be more effective if made out of opaque glassmakers glass, 96 well plates come in glass coated varieties

    If the funding is there, cobalt blue glass vases could be painted over with white. Cobaly blue glass vases could also have all of the English and numbers -1, 0-18 written Letters written on them in glaze. My perception from what JY said is that cobalt
    blue, perhaps also lapis lazuli, is the color of what I call IT pattern resonance effects, that others might call IL. For that reason screening all the letters, numbers, and some shapes with cobalt blue glass, perhaps better with actual cobalt, may have
    higher neural network and mathematical detectable effects than other colors.

    of 700 colors of vases




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    engineering, chemistry, computer ic, computer fab, longevity, longevity technology, treon, treon verdery, physics, lasers, laser, emiconductor, dimension, math, IT, IL, pattern resonance, time travel, chronotechnology, circile, eric the circle, cartoon,
    healthspan, youthspan, cpi, manufacturing, fiscal, money, software, petroleum, archive at deviantart com user treonsebastia

    All technologies, ideas, and inventions of Treon Sebastian Verdery are public domain at JUly 8,2023AD and previously, as well as after that date

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