Source:
https://pubs.rsna.org/doi/10.1148/radiol.241596

<begin abstract>

Abstract

Background

Although measurable organic dysfunctions are frequently absent in
pediatric patients with post–COVID-19 condition (PCC), this condition
adversely affects quality of life. Free-breathing phase-resolved
functional lung (PREFUL) MRI may be useful for assessing lung function
in pediatric patients with PCC.

Purpose

To detect lung changes in children and adolescents with PCC compared
with healthy control participants using PREFUL MRI.

Materials and Methods

In this single-center, prospective, cross-sectional study conducted
between April 2022 and April 2023, children and adolescents (age =17
years) with PCC and age- and sex-matched healthy participants
underwent MRI. Subgroup analysis was performed in participants with
PCC who had cardiopulmonary symptoms. Regional ventilation,
flow-volume loop correlation metric (FVL-CM), quantified perfusion,
ventilation and perfusion defect percentages, and
ventilation-perfusion ratios were compared between participants with
PCC and controls using the Wilcoxon signed rank test. Correlation of
imaging parameters with spirometry, heart rate, respiratory rate, and
Bell score (fatigue severity) in participants with PCC was assessed
using the Spearman rank correlation coefficient.

Results

The final study sample included 54 participants (27 participants with
PCC and 27 matched control participants; median age, 15 years [IQR,
11–17 years]; 14 male participants). Twenty-one participants had cardiopulmonary symptoms. Participants with PCC had lower regional
ventilation (median, 0.2 mL/mL [IQR, 0.1–0.2 mL/mL] vs 0.2 mL/mL [IQR,
0.2–0.2 mL/mL]; P = .047) and quantified perfusion (49 mL/min per 100
mL [IQR, 33–60 mL/min per 100 mL] vs 78 mL/min per 100 mL [IQR, 59–89
mL/min per 100 mL]; P < .001). Participants with PCC and
cardiopulmonary symptoms had lower FVL-CMs (median, 0.99 arbitrary
units [au] [IQR, 0.98–0.99 au] vs 0.99 au [IQR, 0.99–0.99 au]; P =
.01) and higher ventilation defect (median, 7.6% [IQR, 4.5%–15.1%] vs
5.4% [IQR, 2.7%–7.1%]; P = .047) and perfusion defect percentage
(median, 3.2% [IQR, 2.4%–4.2%] vs 2.3% [IQR, 1.8%–3.5%]; P = .02)
compared with matched control participants. In participants with PCC,
greater lung perfusion correlated with increased chronic fatigue
severity (? = 0.48; P = .009) and higher ventilation-perfusion
mismatch correlated with increased heart rate (? = 0.44; P = .02).
Conclusion

Free-breathing phase-resolved functional lung MRI–derived parameters
helped identify a distinct phenotype of lung perfusion in children and adolescents with PCC and were correlated with heart rate and chronic
fatigue severity.

Clinical trial registration no. DRKS00028963

<end abstract>

Source:
https://pubs.rsna.org/doi/10.1148/radiol.241596

In the interim, we are 100% prepared/protected in the "full armor of
GOD" (Ephesians 6:11) which we put on as soon as we use Apostle Paul's
secret (Philippians 4:12). Though masking is less protective, it helps
us avoid the appearance of doing the evil of spreading airborne
pathogens while there are people getting sick because of not being
100% protected. It is written that we're to "abstain from **all**
appearance of doing evil" (1 Thessalonians 5:22 w/**emphasis**).

Meanwhile, the only *perfect* (Matt 5:47-8 ) way to eradicate the
COVID-19 virus, thereby saving lives, in the US & elsewhere is by
rapidly (i.e. use the "Rapid COVID-19 Test" ) finding out at any given
moment, including even while on-line, who among us are unwittingly
contagious (i.e pre-symptomatic or asymptomatic) in order to
"convince it forward" (John 15:12) for them to call their doctor and self-quarantine per their doctor in hopes of stopping this pandemic.
Thus, we're hoping for the best while preparing for the worse-case
scenario of the Alpha lineage mutations and others like the Omicron,
Gamma, Beta, Epsilon, Iota, Lambda, Mu & Delta lineage mutations
combining via slip-RNA-replication to form hybrids like "Deltamicron"
that may render current COVID vaccines/monoclonals/medicines/pills no
longer effective.

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