What is Mounjaro?
Mounjaro is a once-weekly injection that is FDA approved to be used to decrease blood sugar (blood glucose) in adults who have type 2 diabetes. It should be used together with diet and exercise. Mounjaro has also been shown in clinical trials to be
useful for weight loss, however it is currently not an FDA approved weight loss drug.
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Diabetes is a long term condition when your blood sugars (HbA1c) become too high because the body does not produce or use insulin normally. Overtime high blood sugars can cause serious health problems including heart disease, vision loss and kidney
disease.
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Mounjaro works to reduce blood sugar levels by increasing your insulin production and also lowering the amount of sugar your liver makes. It also slows the rate food passes through your body which makes you feel full longer.
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Mounjaro (Tirzepatide) is the first dual GIP/GLP-1 receptor agonist which means it works on the glucose-dependent insulinotropic polypeptide (GIP) receptors and the glucagon-like peptide-1 (GLP-1) receptors.


Mounjaro can be used as a single therapy or with other diabetes medicines including metformin, sulfonylureas or SGLT2 inhibitors.

It is not known if this medicine can be used in people who have had pancreatitis.

Mounjaro is not for use in people with type 1 diabetes.



How should I use Mounjaro?
Mounjaro comes as a solution (liquid) in a pre-filled pen to be injected subcutaneously (under the skin). It is usually given once a week with or without meals at any time of day. Follow the directions on your prescription label carefully, and ask your
doctor or pharmacist to explain any part you do not understand. Use this medicine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
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Your doctor will probably start you on a low dose and gradually increase your dose, not more than once every 4 weeks.

You may change the day of the week you inject this medicine as long as at least 3 days have passed between doses.

You may administer insulin in the same area as Mounjaro but they should not be given right next to each other. Also, you should not mix Mounjaro and insulin in the same injection.
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Mounjaro controls type 2 diabetes but does not cure it. It may take 4 weeks or longer before you feel the full benefit of this medicine. Continue to take this medicine even if you feel well. Do not stop taking this medicine without talking to your doctor.

Mounjaro can be injected in the abdomen, thigh or upper arm. Rotate injection sites with each dose.

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References
What is Diabetes?
Mounjaro FDA Product Label
Lilly Receives U.S. FDA Fast Track Designation for Tirzepatide for the Treatment of Adults with Obesity, or Overweight with Weight-Related Comorbidities
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