RonO wrote:
https://www.cidrap.umn.edu/avian-influenza-bird-flu/hhs-cancels-funding-moderna-s-candidate-h5-avian-flu-and-pandemic-vaccines
This seems stupid since mRNA vaccines would be the fastest way to
respond to H5N1 if it ever does make the jump to human infection. They would need an H5 vaccine that would produce antibodies that could
neutralize the virus. They already know that the virus has changed a
lot in the dairy herd, and they had to make a synthetic antigen with the
H5 genotype B3.13 sequence found in the Missouri patient in order to
look for neutralizing antibodies. They did initial testing on the Texas B3.13 dairy virus and it was neutralized by antibodies produced by H5
vaccine strains that the CDC had, but that obviously changed by the time
the Missouri patient was infected. In the case of the D1.1 genotype
that infected humans they didn't even try to test existing H5 vaccine
strains against it. The D1.1 H5 sequence is very different from the
B3.13 sequence.
This just means that they need to make a vaccine to the virus that might
make the jump to humans. Apparently Moderna had a working vaccine, and
had gotten more funding to work it up, but that has been canceled. For
mRNA vaccines you can make the antigen any sequence that you want it to
be. It is the basis for making updated mRNA vaccines for Covid, and
would be expected to work for influenza. The H5 vaccine that the CDC stockpiled is likely worthless against many of the variants currently infecting cattle and dairy and poultry workers.
Ron Okimoto
Worm-brain Kennedy Jr. is a known anti-vaxxer, and mRNA vaccines hold a
special place in his list of things to eliminate from health care. He's criminally stupid and he's going to get lots of people killed.
Chris
They have Project 2025. We need Project 1792.
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